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Cephradine - Antibiotics - 鹽城鳴遠藥業有限公司、鳴遠藥業、鳴遠藥業有限公司、鹽城鳴遠藥業
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      Cephradine

      CAS number: 38821-53-3

      Molecular formula: C16H19N3O4S

      molecular weight: 349.4048

      Chemical structure:

      Details

      Product Name
      Cefradine
      Shelf Life
      2 years
      Tests
       BP2012 Specifications Results
      Appearance
      White or slightly yellow powder,hygroscopic powder.

      White powder,

      hygroscopic powder.
      Solubility Slightly soluble in water,practically insoluble in ethanol 96 percent and in hexane. Conform
      Identification IR spectrum should match with that of standard Conform
      Clarity of solution Solution S is not more opalescent than reference suspension II
      Conform
      Absorbance at 450nm Not more than 0.6 0.3
      pH
      Between 3.0 and 6.0 4.7
      Specific optical rotation Between +80.0°and +90.0°(anhydrous substance) +85°
      Related substances

      Impurity B Maximum0.25% 0.25%
      Impurities A, C, D, E, F, G Maximum0.25% 0.25%
      Any other impurity Maximum0.5% 0.5%
      Total impurity Maximum2.0% 2.0%
      N,N-Dimethylaniline
      Maximum 20 ppm Not used in process
      Water
      Maximum 6.0%,determined on 0.300 g. 4.3%
      Sulphated ash Maximum 0.2% 0.1%
      Assay

      cefradine Minimum 90.0% 96.8%
      cefalexin Maximum 5.0% 1.5%
      4′,5′-dihydrocefradine Maximum 2.0 % 1.0%
      Sum of cefradine, cefalexin and 4′,5′-dihydrocefradine Minimum 96.0%.and maximum 102.0%(anhydrous substance) 99.3%