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Cefotaxime Sodium - Antibiotics - 鹽城鳴遠藥業有限公司、鳴遠藥業、鳴遠藥業有限公司、鹽城鳴遠藥業
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      Cefotaxime Sodium

      CAS number: 63527-52-6

      Molecular formula: C16H17N5O7S2

      molecular weight: 455.46500

      Chemical structure:

      Details

      Product Name Cefotaxime Sodium
      Shelf life 2 years
      Test items Standard Test results

      Description

      White,off-white to pale yellow crystalline powder,ordorless,or slight special ordor White,crystalline powder slight special ordor
      Clarity and color solution

      1.The solution is clear            

               2.Absorbance0.20

      Conforms                            

            0.08

      Identification

      1.IR spectrum is concordant with RS

      Conforms 

      2.The retention time of the principal peak in HPLC Chromatogram is identical with RS

      Conforms 
      3.It responds to the tests for sodium  Conforms 
      Specific optical rotation +58.0o-+64.0o +60.0o
      pH 4.5-6.5 5.6
      Loss on drying 3.0% 2.1%

      Chromatogram purtiy 

      Individual impurity Total impurities

      1.0%                                

       3.0%

      0.41%                                 

      1.68% 

      Sterility Conforms Conforms
      Bacterial endotoxins 0.20EU/mg Conforms
      Visible particles 0.20EU/mg Conforms
      Particulate matter

      10μm:  2000pc/g

             ≥25μm:  200pc/g

      330pc/g                              

       30pc/g 

      Residue solvent Conforms  Conforms 
      Bulk Density 0.45g/ml 0.47g/ml
      Tapped Density 0.65g/ml 0.68g/ml
      Assay It contains the equivalent of not less than 916μg/mg and not more than 964μg/mg of cefotaxime,C16H17N5O7S2 calculated on the anhydrate basis. 943μg/mg
      CONCLUSION:THE RESULTS CONFORM WITH USP 35 STANDARD